Amfikleia is a town and a former municipality in Phthiotis, Greece. The town is situated at the northern foot of Mount Parnassus, in the valley of the river Cephissus. It is 11 km northwest of Kato Tithorea and 31 km southeast of Lamia. Greek National Road 3 (Thebes - Lamia) passes through the town. It has a railway station on the Athens–Thessaloniki railway. Amfikleia was named after the ancient town Amphicleia. Amphicleia was also named Amphicaea and Ophiteia . It was situated in the north of ancient Phocis. The Persians under Xerxes destroyed the city in 480 BC during the second Persian invasion of Greece. It was rebuilt afterwards, and at the time of Pausanias (2nd century AD), it was known for the worship of Dionysus. The town Dadi, which was founded near the site of ancient Amphicleia, was renamed to Amfikleia in 1915.

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